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Jednotka intenzivní péče je vedená internistou s dvěma atestacemi, současně zde pracuje i kvalifikovaný kardiolog. Její práce spočívá v terapii nemocných s ohroženými základními životními funkcemi. Na interním oddělení jsou hospitalizováni všichni nemocní s krvácením do trávicícho traktu. V centru pozornosti jsou i nemocní s metabolickým rozvratem a onemocněním srdce s výjimkou těch akutních příhod, které řeší oddělení kardiologie v Českých Budějovicích. U všech nemocných klademe značný důraz na enterální a parenterální výživu - terapie je koordinována lékařem v této oblasti plně kvalifikovaným a certifikovaným.
Hemodialyzační středisko ( 7 lůžek) vedené atestovaným nefrologem provádí chronické i akutní hemodialýzy, ve spolupráci s ARO zajišťuje léčení otrav hemoperfúzí. Středisko pracuje ve třech směnách. Akutní hemodialýza a hemoperfúze jsou dostupné 24 hodin denně. V rámci nefrologické ambulance jsou mimo jiné odborně vedeni a kontrolováni nemocní léčení peritoneální dialýzou.
Celá ambulantní část je organizačně i provozně úzce spojena s lůžkovým oddělením. Toto má 6 lůžek intenzivní péče a 61 lůžek standartních. Lůžková část je rozdělena do dvou stanic umístěných v 5. a 6. patře interního pavilonu. Na obou stanicích jsou lůžka umožňující telemetrické sledování EKG. V 5. patře je jeden pokoj vybaven nadstandardně.
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